Fatigue life prediction is one of the most critical engineering disciplines in the automotive industry, affecting both car safety and potential warranty issues. Further, accurate fatigue life predictions support the work to reduce the weight of the car. In the past automotive manufacturers invested billions in the creation of multiple prototypes and physical testing. As technology advanced and computer-aided design and engineering tools became more robust, the car development process shifted from physical to virtual testing. This has led to lower development costs, shorter lead times, and, because more design variants can be examined in the same time frame, higher-quality cars. Key to this paradigm change in the development process is the comprehensive use of the right CAE tools early in the design process, long before the first physical prototype. A good example of successful fatigue simulation usage in the automotive development process is Volvo Car Group (Volvo Cars). Volvo Cars’ CAE teams apply technologies such as nCode DesignLife to predict the fatigue life performance of new cars.